University of California San Francisco

Mark Ratcliffe - 144x - 2
Mark
Ratcliffe
MD
  • Professor of Surgery
  • Division of Adult Cardiothoracic Surgery, UCSF

Address

35 Medical Center Way, #001
San Francisco, CA 94143
United States

Email: [email protected]
Phone: 415-221-4810
Fax: 415-750-2181

Biography

Dr. Ratcliffe received his M.D. degree from Case Western Reserve School of Medicine and completed his General Surgery and Cardiothoracic residencies at the Univeristy of Pennsylvania. Dr. Ratcliffe is certified by the American Board of Surgery and American Board of Thoracic Surgery. His special interest is in the application of finite element analysis or the failing left ventricle. Dr. Ratcliffe has been on the faculty since 1993. Currently, he is Director of the Cardiac Biomechanics Laboratory.

Dr. Ratcliffe is an active member of the American Society for Artificial Internal Organs, American Heart Association, Society of Thoracic Surgeons, Western Thoracic Surgical Association, San Francisco Surgical Society, American Association of Thoracic Surgery, and is a Fellow of the American College of Surgeons.

Education

Education

M.D.-Case Western Reserve University, Cleveland, OHM.D.

B.A. - Denison University, Granville, OH

Residencies

Internship - John Hopkins Hospital, Baltimore, MD

Residency - John Hopkins Hospital, Baltimore, MD

Residency - University of Pennsylvania Hospital, Philadelphia, PA

Research Fellow - University of Pennsylvania Hospital, Philadelphia, PA

Fellowship - University of Pennsylvania Hospital, Philadelphia, PA

Board Certifications

American Board of Surgery, 1989

American Board of Thoracic Surgery, 1993

Clinical Expertise

Minimally invasive cardiac surgery
Off-pump coronary artery bypass surgery
Valve repair and replacement
Surgery for heart failure
Robotic surgery
Thoracic aortic surgery

Grants and Funding

  • Quantitative analysis of left ventriculoplasty: CHF | NIH | 2000-04-17 - 2020-04-30 | Role: Principal Investigator
  • Surgery for Ischemic Mitral Regurgitation | NIH | 2008-01-15 - 2013-12-31 | Role: Principal Investigator

Research Interests

  • Finite element analysis of failing left ventricle

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 122
  1. Imaging in Pulmonary Vascular Disease-Understanding Right Ventricle-Pulmonary Artery Coupling.
    Tsarova K, Morgan AE, Melendres-Groves L, Ibrahim MM, Ma CL, Pan IZ, Hatton ND, Beck EM, Ferrel MN, Selzman CH, Ingram D, Alamri AK, Ratcliffe MB, Wilson BD, Ryan JJ| | PubMed
  2. All Roads Lead to Rome: Diverse Etiologies of Tricuspid Regurgitation Create a Predictable Constellation of Right Ventricular Shape Changes.
    Orkild BA, Zenger B, Iyer K, Rupp LC, Ibrahim MM, Khashani AG, Perez MD, Foote MD, Bergquist JA, Morris AK, Kim JJ, Steinberg BA, Selzman C, Ratcliffe MB, MacLeod RS, Elhabian S, Morgan AE| | PubMed
  3. A finite element model of the cardiac ventricles with coupled circulation: Biventricular mesh generation with hexahedral elements, airbags and a functional mockup interface to the circulation.
    Zhang Y, Adams J, Wang VY, Horwitz L, Tartibi M, Morgan AE, Kim J, Wallace AW, Weinsaft JW, Ge L, Ratcliffe MB| | PubMed
  4. A kinematic model-based analysis framework for 3D Cine-DENSE-validation with an axially compressed gel phantom and application in sheep before and after antero-apical myocardial infarction.
    Wang VY, Tartibi M, Zhang Y, Selvaganesan K, Haraldsson H, Auger DA, Faraji F, Spaulding K, Takaba K, Collins A, Aguayo E, Saloner D, Wallace AW, Weinsaft JW, Epstein FH, Guccione J, Ge L, Ratcliffe MB| | PubMed
  5. Finite-element based optimization of left ventricular passive stiffness in normal volunteers and patients after myocardial infarction: Utility of an inverse deformation gradient calculation of regional diastolic strain.
    Zhang Y, Wang VY, Morgan AE, Kim J, Tafreshi R, Wallace AW, Guccione JM, Weinsaft JW, Ge L, Ratcliffe MB| | PubMed
  6. Ischemia-Mediated Dysfunction in Subpapillary Myocardium as a Marker of Functional Mitral Regurgitation.
    Kochav JD, Kim J, Judd R, Kim HW, Klem I, Heitner J, Shah D, Shenoy C, Farzaneh-Far A, Polsani V, Kalil R, Villar-Calle P, Nambiar L, Sultana R, Parker M, Cargile P, Khalique OK, Leon MB, Karmpaliotis D, Ratcliffe M, Levine R, Zoghbi WA, Devereux RB, Moskowitz CS, Kim R, Weinsaft JW| | PubMed
  7. Right Ventricular Shape Distortion in Tricuspid Regurgitation.
    Morgan AE, Kashani A, Zenger B, Rupp LC, Perez MD, Foote MD, Morris AK, Ratcliffe MB, Kim JJ, Weinsaft JW, Sharma V, MacLeod RS, Elhabian S| | PubMed
  8. Left ventricular geometry during unloading and the end-systolic pressure volume relationship: Measurement with a modified real-time MRI-based method in normal sheep.
    Giao DM, Wang Y, Rojas R, Takaba K, Badathala A, Spaulding KA, Soon G, Zhang Y, Wang VY, Haraldsson H, Liu J, Saloner D, Guccione JM, Ge L, Wallace AW, Ratcliffe MB| | PubMed
  9. Myocardial injection of a thermoresponsive hydrogel with reactive oxygen species scavenger properties improves border zone contractility.
    Spaulding KA, Zhu Y, Takaba K, Ramasubramanian A, Badathala A, Haraldsson H, Collins A, Aguayo E, Shah C, Wallace AW, Ziats NP, Lovett DH, Baker AJ, Healy KE, Ratcliffe MB| | PubMed
  10. A Novel MRI-Based Finite Element Modeling Method for Calculation of Myocardial Ischemia Effect in Patients With Functional Mitral Regurgitation.
    Zhang Y, Wang VY, Morgan AE, Kim J, Ge L, Guccione JM, Weinsaft JW, Ratcliffe MB| | PubMed
122
View all 122 Publications
MOST RECENT PUBLICATIONS FROM A TOTAL OF 122
  1. Imaging in Pulmonary Vascular Disease-Understanding Right Ventricle-Pulmonary Artery Coupling.
    Tsarova K, Morgan AE, Melendres-Groves L, Ibrahim MM, Ma CL, Pan IZ, Hatton ND, Beck EM, Ferrel MN, Selzman CH, Ingram D, Alamri AK, Ratcliffe MB, Wilson BD, Ryan JJ| | PubMed
  2. All Roads Lead to Rome: Diverse Etiologies of Tricuspid Regurgitation Create a Predictable Constellation of Right Ventricular Shape Changes.
    Orkild BA, Zenger B, Iyer K, Rupp LC, Ibrahim MM, Khashani AG, Perez MD, Foote MD, Bergquist JA, Morris AK, Kim JJ, Steinberg BA, Selzman C, Ratcliffe MB, MacLeod RS, Elhabian S, Morgan AE| | PubMed
  3. A finite element model of the cardiac ventricles with coupled circulation: Biventricular mesh generation with hexahedral elements, airbags and a functional mockup interface to the circulation.
    Zhang Y, Adams J, Wang VY, Horwitz L, Tartibi M, Morgan AE, Kim J, Wallace AW, Weinsaft JW, Ge L, Ratcliffe MB| | PubMed
  4. A kinematic model-based analysis framework for 3D Cine-DENSE-validation with an axially compressed gel phantom and application in sheep before and after antero-apical myocardial infarction.
    Wang VY, Tartibi M, Zhang Y, Selvaganesan K, Haraldsson H, Auger DA, Faraji F, Spaulding K, Takaba K, Collins A, Aguayo E, Saloner D, Wallace AW, Weinsaft JW, Epstein FH, Guccione J, Ge L, Ratcliffe MB| | PubMed
  5. Finite-element based optimization of left ventricular passive stiffness in normal volunteers and patients after myocardial infarction: Utility of an inverse deformation gradient calculation of regional diastolic strain.
    Zhang Y, Wang VY, Morgan AE, Kim J, Tafreshi R, Wallace AW, Guccione JM, Weinsaft JW, Ge L, Ratcliffe MB| | PubMed
  6. Ischemia-Mediated Dysfunction in Subpapillary Myocardium as a Marker of Functional Mitral Regurgitation.
    Kochav JD, Kim J, Judd R, Kim HW, Klem I, Heitner J, Shah D, Shenoy C, Farzaneh-Far A, Polsani V, Kalil R, Villar-Calle P, Nambiar L, Sultana R, Parker M, Cargile P, Khalique OK, Leon MB, Karmpaliotis D, Ratcliffe M, Levine R, Zoghbi WA, Devereux RB, Moskowitz CS, Kim R, Weinsaft JW| | PubMed
  7. Right Ventricular Shape Distortion in Tricuspid Regurgitation.
    Morgan AE, Kashani A, Zenger B, Rupp LC, Perez MD, Foote MD, Morris AK, Ratcliffe MB, Kim JJ, Weinsaft JW, Sharma V, MacLeod RS, Elhabian S| | PubMed
  8. Left ventricular geometry during unloading and the end-systolic pressure volume relationship: Measurement with a modified real-time MRI-based method in normal sheep.
    Giao DM, Wang Y, Rojas R, Takaba K, Badathala A, Spaulding KA, Soon G, Zhang Y, Wang VY, Haraldsson H, Liu J, Saloner D, Guccione JM, Ge L, Wallace AW, Ratcliffe MB| | PubMed
  9. Myocardial injection of a thermoresponsive hydrogel with reactive oxygen species scavenger properties improves border zone contractility.
    Spaulding KA, Zhu Y, Takaba K, Ramasubramanian A, Badathala A, Haraldsson H, Collins A, Aguayo E, Shah C, Wallace AW, Ziats NP, Lovett DH, Baker AJ, Healy KE, Ratcliffe MB| | PubMed
  10. A Novel MRI-Based Finite Element Modeling Method for Calculation of Myocardial Ischemia Effect in Patients With Functional Mitral Regurgitation.
    Zhang Y, Wang VY, Morgan AE, Kim J, Ge L, Guccione JM, Weinsaft JW, Ratcliffe MB| | PubMed
  11. Transcatheter MitraClip repair alters mitral annular geometry - device induced annular remodeling on three-dimensional echocardiography predicts therapeutic response.
    Kim J, Palumbo MC, Khalique OK, Rong LQ, Sultana R, Das M, Jantz J, Nagata Y, Devereux RB, Wong SC, Bergman GW, Levine RA, Ratcliffe MB, Weinsaft JW| | PubMed
  12. Mechanical effects of MitraClip on leaflet stress and myocardial strain in functional mitral regurgitation - A finite element modeling study.
    Zhang Y, Wang VY, Morgan AE, Kim J, Handschumacher MD, Moskowitz CS, Levine RA, Ge L, Guccione JM, Weinsaft JW, Ratcliffe MB| | PubMed
  13. Impact of Mitral Regurgitation Severity and Cause on Effort Tolerance-Integrated Stress Myocardial Perfusion Imaging and Echocardiographic Assessment of Patients With Known or Suspected Coronary Artery Disease Undergoing Exercise Treadmill Testing.
    Kampaktsis PN, Albert BJ, Kim J, Xie LX, Brouwer LR, Tehrani NH, Villanueva M, Choi DY, Szulc M, Ratcliffe MB, Levine RA, Devereux RB, Weinsaft JW| | PubMed
  14. Left ventricular geometry predicts optimal response to percutaneous mitral repair via MitraClip: Integrated assessment by two- and three-dimensional echocardiography.
    Kim J, Alakbarli J, Palumbo MC, Xie LX, Rong LQ, Tehrani NH, Brouwer LR, Devereux RB, Wong SC, Bergman GW, Khalique OK, Levine RA, Ratcliffe MB, Weinsaft JW| | PubMed
  15. Tissue-based markers of right ventricular dysfunction in ischemic mitral regurgitation assessed via stress cardiac magnetic resonance and three-dimensional echocardiography.
    Kim J, Alakbarli J, Yum B, Tehrani NH, Pollie MP, Abouzeid C, Di Franco A, Ratcliffe MB, Poppas A, Levine RA, Devereux RB, Weinsaft JW| | PubMed
  16. Short term doxycycline treatment induces sustained improvement in myocardial infarction border zone contractility.
    Spaulding K, Takaba K, Collins A, Faraji F, Wang G, Aguayo E, Ge L, Saloner D, Wallace AW, Baker AJ, Lovett DH, Ratcliffe MB| | PubMed
  17. Correction to: Abstracts : 29th European Congress of Pathology.
    Al-Masri H, Ratcliffe M, Sharpe A, Barker C, Scorer P, Scott M, Rebelatto M, Walker J| | PubMed
  18. Ischemic Mitral Regurgitation: Abnormal Strain Overestimates Nonviable Myocardium.
    Morgan AE, Zhang Y, Tartibi M, Goldburg S, Kim JJ, Nguyen TD, Guccione J, Ge L, Weinsaft JW, Ratcliffe MB| | PubMed
  19. Multiplanar strain quantification for assessment of right ventricular dysfunction and non-ischemic fibrosis among patients with ischemic mitral regurgitation.
    Di Franco A, Kim J, Rodriguez-Diego S, Khalique O, Siden JY, Goldburg SR, Mehta NK, Srinivasan A, Ratcliffe MB, Levine RA, Crea F, Devereux RB, Weinsaft JW| | PubMed
  20. Echocardiography-quantified myocardial strain-a marker of global and regional infarct size that stratifies likelihood of left ventricular thrombus.
    Kim J, Rodriguez-Diego S, Srinivasan A, Brown RM, Pollie MP, Di Franco A, Goldburg SR, Siden JY, Ratcliffe MB, Levine RA, Devereux RB, Weinsaft JW| | PubMed
  21. Association of Uneven MitraClip Application and Leaflet Stress in a Finite Element Model.
    Morgan AE, Wozniak CJ, Gulati S, Ge L, Grossi EA, Weinsaft JW, Ratcliffe MB| | PubMed
  22. Right Ventricular Dysfunction Impairs Effort Tolerance Independent of Left Ventricular Function Among Patients Undergoing Exercise Stress Myocardial Perfusion Imaging.
    Kim J, Di Franco A, Seoane T, Srinivasan A, Kampaktsis PN, Geevarghese A, Goldburg SR, Khan SA, Szulc M, Ratcliffe MB, Levine RA, Morgan AE, Maddula P, Rozenstrauch M, Shah T, Devereux RB, Weinsaft JW| | PubMed
  23. Undersized Mitral Annuloplasty Increases Strain in the Proximal Lateral Left Ventricular Wall.
    Pantoja JL, Morgan AE, Grossi EA, Jensen MO, Weinsaft JW, Levine RA, Ge L, Ratcliffe MB| | PubMed
  24. Neochord placement versus triangular resection in mitral valve repair: A finite element model.
    Morgan AE, Pantoja JL, Grossi EA, Ge L, Weinsaft JW, Ratcliffe MB| | PubMed
  25. Suture Forces for Closure of Transapical Transcatheter Aortic Valve Replacement: A Mathematical Model.
    Ge L, Haraldsson H, Hope MD, Saloner D, Guccione JM, Ratcliffe MB, Tseng EE| | PubMed
  26. Moderate Ischemic Mitral Regurgitation After Posterolateral Myocardial Infarction in Sheep Alters Left Ventricular Shear but Not Normal Strain in the Infarct and Infarct Borderzone.
    Ge L, Wu Y, Soleimani M, Khazalpour M, Takaba K, Tartibi M, Zhang Z, Acevedo-Bolton G, Saloner DA, Wallace AW, Mishra R, Grossi EA, Guccione JM, Ratcliffe MB| | PubMed
  27. Finite Element Modeling of Mitral Valve Repair.
    Morgan AE, Pantoja JL, Weinsaft J, Grossi E, Guccione JM, Ge L, Ratcliffe M| | PubMed
  28. Myocardial perfusion pattern for stratification of ischemic mitral regurgitation response to percutaneous coronary intervention.
    Goyal P, Kim J, Feher A, Ma CL, Gurevich S, Veal DR, Szulc M, Wong FJ, Ratcliffe MB, Levine RA, Devereux RB, Weinsaft JW| | PubMed
  29. Residual Stress Impairs Pump Function After Surgical Ventricular Remodeling: A Finite Element Analysis.
    Pantoja JL, Zhang Z, Tartibi M, Sun K, Macmillan W, Guccione JM, Ge L, Ratcliffe MB| | PubMed
  30. Progressive design concepts in off-pump left ventricular remodeling mitral valve repair devices.
    Yaffee DW, Grossi EA, Ratcliffe MB| | PubMed
  31. Studies on postinfarct left ventricular remodeling: state of the art.
    Ratcliffe M, Cambronero N, Takaba K, Ge L| | PubMed
  32. Effect of mitral annuloplasty device shape and size on leaflet and myofiber stress following repair of posterior leaflet prolapse: a patient-specific finite element simulation.
    Morrel WG, Ge L, Zhang Z, Grossi EA, Guccione JM, Ratcliffe MB| | PubMed
  33. A N-terminal truncated intracellular isoform of matrix metalloproteinase-2 impairs contractility of mouse myocardium.
    Lovett DH, Chu C, Wang G, Ratcliffe MB, Baker AJ| | PubMed
  34. Myofilament dysfunction contributes to impaired myocardial contraction in the infarct border zone.
    Shimkunas R, Makwana O, Spaulding K, Bazargan M, Khazalpour M, Takaba K, Soleimani M, Myagmar BE, Lovett DH, Simpson PC, Ratcliffe MB, Baker AJ| | PubMed
  35. Posterior papillary muscle anchoring affects remote myofiber stress and pump function: finite element analysis.
    Pantoja JL, Ge L, Zhang Z, Morrel WG, Guccione JM, Grossi EA, Ratcliffe MB| | PubMed
  36. Patient-specific finite element modeling of the Cardiokinetix Parachute(®) device: effects on left ventricular wall stress and function.
    Lee LC, Ge L, Zhang Z, Pease M, Nikolic SD, Mishra R, Ratcliffe MB, Guccione JM| | PubMed
  37. Invited commentary.
    Ratcliffe M, Cambronero N, Long S| | PubMed
  38. Applications of computational modeling in cardiac surgery.
    Lee LC, Genet M, Dang AB, Ge L, Guccione JM, Ratcliffe MB| | PubMed
  39. Measurement of mitral leaflet and annular geometry and stress after repair of posterior leaflet prolapse: virtual repair using a patient-specific finite element simulation.
    Ge L, Morrel WG, Ward A, Mishra R, Zhang Z, Guccione JM, Grossi EA, Ratcliffe MB| | PubMed
  40. Invited commentary.
    Ratcliffe MB, Wozniak CJ| | PubMed
  41. Analysis of patient-specific surgical ventricular restoration: importance of an ellipsoidal left ventricular geometry for diastolic and systolic function.
    Lee LC, Wenk JF, Zhong L, Klepach D, Zhang Z, Ge L, Ratcliffe MB, Zohdi TI, Hsu E, Navia JL, Kassab GS, Guccione JM| | PubMed
  42. Biventricular finite element modeling of the Acorn CorCap Cardiac Support Device on a failing heart.
    Wenk JF, Ge L, Zhang Z, Mojsejenko D, Potter DD, Tseng EE, Guccione JM, Ratcliffe MB| | PubMed
  43. Left ventricular myocardial contractility is depressed in the borderzone after posterolateral myocardial infarction.
    Shimkunas R, Zhang Z, Wenk JF, Soleimani M, Khazalpour M, Acevedo-Bolton G, Wang G, Saloner D, Mishra R, Wallace AW, Ge L, Baker AJ, Guccione JM, Ratcliffe MB| | PubMed
  44. Left ventricular pressure gating in ovine cardiac studies: a software-based method.
    Acevedo-Bolton G, Suzuki T, Malhotra D, Zhang Z, Wallace AW, Guccione JM, Saloner DA, Ratcliffe MB| | PubMed
  45. Invited commentary.
    Ratcliffe M, Cambronero N, Ge L| | PubMed
  46. Finite element modeling of mitral leaflet tissue using a layered shell approximation.
    Wenk JF, Ratcliffe MB, Guccione JM| | PubMed
  47. Material properties of CorCap passive cardiac support device.
    Chitsaz S, Wenk JF, Ge L, Wisneski A, Mookhoek A, Ratcliffe MB, Guccione JM, Tseng EE| | PubMed
  48. Patient-specific finite element-based analysis of ventricular myofiber stress after Coapsys: importance of residual stress.
    Carrick R, Ge L, Lee LC, Zhang Z, Mishra R, Axel L, Guccione JM, Grossi EA, Ratcliffe MB| | PubMed
  49. The benefit of enhanced contractility in the infarct borderzone: a virtual experiment.
    Zhang Z, Sun K, Saloner DA, Wallace AW, Ge L, Baker AJ, Guccione JM, Ratcliffe MB| | PubMed
  50. Growth and remodeling of the left ventricle: A case study of myocardial infarction and surgical ventricular restoration.
    Klepach D, Lee LC, Wenk JF, Ratcliffe MB, Zohdi TI, Navia JA, Kassab GS, Kuhl E, Guccione JM| | PubMed
  51. A coupled biventricular finite element and lumped-parameter circulatory system model of heart failure.
    Wenk JF, Ge L, Zhang Z, Soleimani M, Potter DD, Wallace AW, Tseng E, Ratcliffe MB, Guccione JM| | PubMed
  52. The effect of mitral annuloplasty shape in ischemic mitral regurgitation: a finite element simulation.
    Wong VM, Wenk JF, Zhang Z, Cheng G, Acevedo-Bolton G, Burger M, Saloner DA, Wallace AW, Guccione JM, Ratcliffe MB, Ge L| | PubMed
  53. Electromechanical feedback with reduced cellular connectivity alters electrical activity in an infarct injured left ventricle: a finite element model study.
    Wall ST, Guccione JM, Ratcliffe MB, Sundnes JS| | PubMed
  54. Invited commentary.
    Wenk J, Guccione J, Ratcliffe M| | PubMed
  55. Moderate mitral regurgitation accelerates left ventricular remodeling after posterolateral myocardial infarction.
    Soleimani M, Khazalpour M, Cheng G, Zhang Z, Acevedo-Bolton G, Saloner DA, Mishra R, Wallace AW, Guccione JM, Ge L, Ratcliffe MB| | PubMed
  56. A novel method for quantifying in-vivo regional left ventricular myocardial contractility in the border zone of a myocardial infarction.
    Lee LC, Wenk JF, Klepach D, Zhang Z, Saloner D, Wallace AW, Ge L, Ratcliffe MB, Guccione JM| | PubMed
  57. A novel method for quantifying the in-vivo mechanical effect of material injected into a myocardial infarction.
    Wenk JF, Eslami P, Zhang Z, Xu C, Kuhl E, Gorman JH, Robb JD, Ratcliffe MB, Gorman RC, Guccione JM| | PubMed
  58. Operative risks and survival in veterans with severe aortic stenosis: surgery versus medical therapy.
    Chitsaz S, Jaussaud N, Chau E, Yan KS, Azadani AN, Ratcliffe MB, Tseng EE| | PubMed
  59. Invited commentary.
    Mishra RK, Ratcliffe M| | PubMed
  60. Regional left ventricular myocardial contractility and stress in a finite element model of posterobasal myocardial infarction.
    Wenk JF, Sun K, Zhang Z, Soleimani M, Ge L, Saloner D, Wallace AW, Ratcliffe MB, Guccione JM| | PubMed
  61. Comparison of the Young-Laplace law and finite element based calculation of ventricular wall stress: implications for postinfarct and surgical ventricular remodeling.
    Zhang Z, Tendulkar A, Sun K, Saloner DA, Wallace AW, Ge L, Guccione JM, Ratcliffe MB| | PubMed
  62. First finite element model of the left ventricle with mitral valve: insights into ischemic mitral regurgitation.
    Wenk JF, Zhang Z, Cheng G, Malhotra D, Acevedo-Bolton G, Burger M, Suzuki T, Saloner DA, Wallace AW, Guccione JM, Ratcliffe MB| | PubMed
  63. Dor procedure for dyskinetic anteroapical myocardial infarction fails to improve contractility in the border zone.
    Sun K, Zhang Z, Suzuki T, Wenk JF, Stander N, Einstein DR, Saloner DA, Wallace AW, Guccione JM, Ratcliffe MB| | PubMed
  64. Fluid-Structure Interactions of the Mitral Valve and Left Heart: Comprehensive Strategies, Past, Present and Future.
    Einstein DR, Del Pin F, Jiao X, Kuprat AP, Carson JP, Kunzelman KS, Cochran RP, Guccione JM, Ratcliffe MB| | PubMed
  65. Severe aortic stenosis in a veteran population: treatment considerations and survival.
    Bakaeen FG, Chu D, Ratcliffe M, Gopaldas RR, Blaustein AS, Venkat R, Huh J, LeMaire SA, Coselli JS, Carabello BA| | PubMed
  66. Effect of adjustable passive constraint on the failing left ventricle: a finite-element model study.
    Jhun CS, Wenk JF, Zhang Z, Wall ST, Sun K, Sabbah HN, Ratcliffe MB, Guccione JM| | PubMed
  67. A method for automatically optimizing medical devices for treating heart failure: designing polymeric injection patterns.
    Wenk JF, Wall ST, Peterson RC, Helgerson SL, Sabbah HN, Burger M, Stander N, Ratcliffe MB, Guccione JM| | PubMed
  68. A computationally efficient formal optimization of regional myocardial contractility in a sheep with left ventricular aneurysm.
    Sun K, Stander N, Jhun CS, Zhang Z, Suzuki T, Wang GY, Saeed M, Wallace AW, Tseng EE, Baker AJ, Saloner D, Einstein DR, Ratcliffe MB, Guccione JM| | PubMed
  69. Adaptive generation of multimaterial grids from imaging data for biomedical Lagrangian fluid-structure simulations.
    Carson JP, Kuprat AP, Jiao X, Dyedov V, Del Pin F, Guccione JM, Ratcliffe MB, Einstein DR| | PubMed
  70. The use of computational flow modeling (CFD) to determine the effect of left ventricular shape on blood flow in the left ventricle.
    Ge L, Ratcliffe M| | PubMed
  71. The biomechanics of arterial elastin.
    Gundiah N, Ratcliffe MB, Pruitt LA| | PubMed
  72. A simple correction for anomalous coronary arteries in adults.
    Guy TS, Tseng E, Ratcliffe MB, Azakie A, Karl TR| | PubMed
  73. National Institutes of Health funding for cardiothoracic surgical research.
    Ratcliffe MB, Howard C, Mann M, del Nido P| | PubMed
  74. Asymmetric mechanical properties of porcine aortic sinuses.
    Gundiah N, Kam K, Matthews PB, Guccione J, Dwyer HA, Saloner D, Chuter TA, Guy TS, Ratcliffe MB, Tseng EE| | PubMed
  75. Magnetic resonance imaging-based finite element stress analysis after linear repair of left ventricular aneurysm.
    Walker JC, Ratcliffe MB, Zhang P, Wallace AW, Hsu EW, Saloner DA, Guccione JM| | PubMed
  76. National institutes of health funding for surgical research.
    Mann M, Tendulkar A, Birger N, Howard C, Ratcliffe MB| | PubMed
  77. Cost-utility analysis of treatment with olanzapine compared with other antipsychotic treatments in patients with schizophrenia in the pan-European SOHO study.
    Knapp M, Windmeijer F, Brown J, Kontodimas S, Tzivelekis S, Haro JM, Ratcliffe M, Hong J, Novick D, SOHO Study Group| | PubMed
  78. Endoventricular patch plasty for dyskinetic anteroapical left ventricular aneurysm increases systolic circumferential shortening in sheep.
    Zhang P, Guccione JM, Nicholas SI, Walker JC, Crawford PC, Shamal A, Acevedo-Bolton G, Guttman MA, Ozturk C, McVeigh ER, Saloner DA, Wallace AW, Ratcliffe MB| | PubMed
  79. The effect of preoperative diastolic dysfunction on outcome after surgical ventricular remodeling.
    Ratcliffe MB, Guy TS| | PubMed
  80. Invited commentary.
    Ratcliffe MB| | PubMed
  81. Transmural heterogeneity of diffusion anisotropy in the sheep myocardium characterized by MR diffusion tensor imaging.
    Jiang Y, Guccione JM, Ratcliffe MB, Hsu EW| | PubMed
  82. Remission and relapse in the outpatient care of schizophrenia: three-year results from the Schizophrenia Outpatient Health Outcomes study.
    Haro JM, Novick D, Suarez D, Alonso J, Lépine JP, Ratcliffe M, SOHO Study Group| | PubMed
  83. Theoretical impact of the injection of material into the myocardium: a finite element model simulation.
    Wall ST, Walker JC, Healy KE, Ratcliffe MB, Guccione JM| | PubMed
  84. The treatment of ischemic heart failure with surgical ventricular restoration (SVR): new evidence of benefit.
    Ratcliffe MB| | PubMed
  85. The effect of anteroapical aneurysm plication on end-systolic three-dimensional strain in the sheep: a magnetic resonance imaging tagging study.
    Guccione JM, Walker JC, Beitler JR, Moonly SM, Zhang P, Guttman MA, Ozturk C, McVeigh ER, Wallace AW, Saloner DA, Ratcliffe MB| | PubMed
  86. Left ventricular volume and function after endoventricular patch plasty for dyskinetic anteroapical left ventricular aneurysm in sheep.
    Zhang P, Guccione JM, Nicholas SI, Walker JC, Crawford PC, Shamal A, Saloner DA, Wallace AW, Ratcliffe MB| | PubMed
  87. MRI-based finite-element analysis of left ventricular aneurysm.
    Walker JC, Ratcliffe MB, Zhang P, Wallace AW, Fata B, Hsu EW, Saloner D, Guccione JM| | PubMed
  88. Helical myofiber orientation after myocardial infarction and left ventricular surgical restoration in sheep.
    Walker JC, Guccione JM, Jiang Y, Zhang P, Wallace AW, Hsu EW, Ratcliffe MB| | PubMed
  89. Use of bivalirudin, a direct thrombin inhibitor, and its reversal with modified ultrafiltration during heart transplantation in a patient with heparin-induced thrombocytopenia.
    Mann MJ, Tseng E, Ratcliffe M, Strattman G, De Silva A, Demarco T, Achorn N, Moskalik W, Hoopes C| | PubMed
  90. Effect of ventricular size and patch stiffness in surgical anterior ventricular restoration: a finite element model study.
    Dang AB, Guccione JM, Zhang P, Wallace AW, Gorman RC, Gorman JH, Ratcliffe MB| | PubMed
  91. Akinetic myocardial infarcts must contain contracting myocytes: finite-element model study.
    Dang AB, Guccione JM, Mishell JM, Zhang P, Wallace AW, Gorman RC, Gorman JH, Ratcliffe MB| | PubMed
  92. Myosplint decreases wall stress without depressing function in the failing heart: a finite element model study.
    Guccione JM, Salahieh A, Moonly SM, Kortsmit J, Wallace AW, Ratcliffe MB| | PubMed
  93. Effect of preoperative delay on prognosis for patients with early stage non-small cell lung cancer.
    Quarterman RL, McMillan A, Ratcliffe MB, Block MI| | PubMed
  94. A finite element model of left ventricular cellular transplantation in dilated cardiomyopathy.
    Quarterman RL, Moonly S, Wallace AW, Guccione J, Ratcliffe MB| | PubMed
  95. Ventricular remodeling surgery for heart failure: small animals and how to measure an improvement in ventricular function.
    Teerlink JR, Ratcliffe MB| | PubMed
  96. Left ventricular volume reduction by radiofrequency heating of chronic myocardial infarction in patients with congestive heart failure.
    Victal OA, Teerlink JR, Gaxiola E, Wallace AW, Najar S, Camacho DH, Gutierrez A, Herrera G, Zuniga G, Mercado-Rios F, Ratcliffe MB| | PubMed
  97. Residual stress produced by ventricular volume reduction surgery has little effect on ventricular function and mechanics: a finite element model study.
    Guccione JM, Moonly SM, Wallace AW, Ratcliffe MB| | PubMed
  98. Cardiopulmonary Complications Following Cardiac Surgery.
    Quarterman RL, Wallace A, Ratcliffe MB| | PubMed
  99. Mechanism underlying mechanical dysfunction in the border zone of left ventricular aneurysm: a finite element model study.
    Guccione JM, Moonly SM, Moustakidis P, Costa KD, Moulton MJ, Ratcliffe MB, Pasque MK| | PubMed
  100. Batista's operation: what have we learned?
    Ratcliffe M| | PubMed
  101. Effect of induction and reperfusion with warm substrate-enriched cardioplegia on ventricular function.
    Wallace AW, Ratcliffe MB, Nosé PS, Bellows W, Moores W, McEnany MT, Flachsbart K, Mangano DT| | PubMed
  102. Collection of process data after cardiac surgery: initial implementation with a Java-based intranet applet.
    Ratcliffe MB, Khan JH, Magee KM, McElhinney DB, Hubner C| | PubMed
  103. Radio frequency heating of chronic ovine infarct leads to sustained infarct area and ventricular volume reduction.
    Ratcliffe MB, Wallace AW, Teerlink JR, Hong J, Salahieh A, Sung SH, Keung EC, Lee RJ| | PubMed
  104. The effect of diastolic stiffness on ventricular function after partial ventriculectomy: a finite element simulation.
    Ratcliffe MB, Hong J, Salahieh A, Wallace AW| | PubMed
  105. Ventricular volume, chamber stiffness, and function after anteroapical aneurysm plication in the sheep.
    Ratcliffe MB, Wallace AW, Salahieh A, Hong J, Ruch S, Hall TS| | PubMed
  106. L-arginine infusion dilates coronary vasculature in patients undergoing coronary bypass surgery.
    Wallace AW, Ratcliffe MB, Galindez D, Kong JS| | PubMed
  107. The effect of ventricular volume reduction surgery in the dilated, poorly contractile left ventricle: a simple finite element analysis.
    Ratcliffe MB, Hong J, Salahieh A, Ruch S, Wallace AW| | PubMed
  108. Dynamic three-dimensional imaging of the mitral valve and left ventricle by rapid sonomicrometry array localization.
    Gorman JH, Gupta KB, Streicher JT, Gorman RC, Jackson BM, Ratcliffe MB, Bogen DK, Edmunds LH| | PubMed
  109. Use of sonomicrometry and multidimensional scaling to determine the three-dimensional coordinates of multiple cardiac locations: feasibility and initial implementation.
    Ratcliffe MB, Gupta KB, Streicher JT, Savage EB, Bogen DK, Edmunds LH| | PubMed
  110. Pathogenesis of acute ischemic mitral regurgitation in three dimensions.
    Gorman RC, McCaughan JS, Ratcliffe MB, Gupta KB, Streicher JT, Ferrari VA, St John-Sutton MG, Bogen DK, Edmunds LH| | PubMed
  111. A novel sialyl LewisX analog attenuates neutrophil accumulation and myocardial necrosis after ischemia and reperfusion.
    Lefer DJ, Flynn DM, Phillips ML, Ratcliffe M, Buda AJ| | PubMed
  112. Changes in passive mechanical stiffness of myocardial tissue with aneurysm formation.
    Gupta KB, Ratcliffe MB, Fallert MA, Edmunds LH, Bogen DK| | PubMed
  113. Left ventricular assist without thoracotomy: clinical experience with the Dennis method.
    Edmunds LH, Herrmann HC, DiSesa VJ, Ratcliffe MB, Bavaria JE, McCarthy DM| | PubMed
  114. Large animal model of ischemic mitral regurgitation.
    Llaneras MR, Nance ML, Streicher JT, Lima JA, Savino JS, Bogen DK, Deac RF, Ratcliffe MB, Edmunds LH| | PubMed
  115. Repair of left ventricular aneurysm. Changes in ventricular mechanics, hemodynamics, and oxygen consumption.
    Savage EB, Downing SW, Ratcliffe MB, Fallert M, Gupta KB, Tyson GS, Bogen DK, Edmunds LH| | PubMed
  116. Left ventricular mechanics of ejecting, postischemic hearts during left ventricular circulatory assistance.
    Ratcliffe MB, Bavaria JE, Wenger RK, Bogen DK, Edmunds LH| | PubMed
  117. Myocardial oxygen utilization after reversible global ischemia.
    Bavaria JE, Furukawa S, Kreiner G, Ratcliffe MB, Streicher J, Bogen DK, Edmunds LH| | PubMed
  118. Large animal model of left ventricular aneurysm.
    Markovitz LJ, Savage EB, Ratcliffe MB, Bavaria JE, Kreiner G, Iozzo RV, Hargrove WC, Bogen DK, Edmunds LH| | PubMed
  119. Measurement of end-systolic pressure-volume relations by intra-aortic balloon occlusion.
    Gupta KB, Bavaria JE, Ratcliffe MB, Edmunds LH, Bogen DK| | PubMed
  120. Surgery for left ventricular aneurysm. Early survival with and without endocardial resection.
    Stephenson LW, Hargrove WC, Ratcliffe MB, Edmunds LH| | PubMed
  121. Flow dynamics of peripheral venous catheters during extracorporeal membrane oxygenation with a centrifugal pump.
    Wenger RK, Bavaria JE, Ratcliffe MB, Bogen D, Edmunds LH| | PubMed
  122. Changes in left ventricular systolic wall stress during biventricular circulatory assistance.
    Bavaria JE, Ratcliffe MB, Gupta KB, Wenger RK, Bogen DK, Edmunds LH| | PubMed